Vulnerability Description
OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.
Related Weaknesses (CWE)
References
- https://github.com/openslide/openslide-bin/issues/433
- https://github.com/openslide/openslide-bin/pull/436
- https://github.com/openslide/openslide/commit/a4f0fb0ec462edcea97ff22288f606ac6c
- https://github.com/openslide/openslide/pull/706
- https://github.com/openslide/openslide/releases/tag/v4.0.1
- https://github.com/openslide/openslide/security/advisories/GHSA-f734-jv98-5677
- https://gitlab.com/libtiff/libtiff/-/work_items/791
FAQ
What is CVE-2026-54604?
CVE-2026-54604 is a documented vulnerability. OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_r...
How severe is CVE-2026-54604?
CVSS scoring is not yet available for CVE-2026-54604. Check NVD for updates.
Is there a patch for CVE-2026-54604?
Check the references section above for vendor advisories and patch information. Review vendor security bulletins for remediation guidance.